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Causes of Ataxia in Adults
Non-inherited
- Brain lesion or tumor
- Toxins: aminoglycoside antibiotics, lead, sedatives, anticonvulsants, alcohol
- Infection: HIV, syphilis, prion disease
- Paraneoplastic syndrome
- Multiple system atrophy-cerebellar form
- Vitamin E deficiency (due to malabsorption)
- Multiple sclerosis
Inherited
- Friedreich ataxia
- Spinocerebellar ataxia (types 1-28)
- Episodic ataxia (type 1, type 2)
- Fragile X tremor/ataxia syndrome
- Dentatorubro-pallidoluysian atrophy
- Vitamin E deficiency
- Wilson's disease
- Metabolic disorders
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